Blood-Brain Barrier (BBB) The two important measures of quality and efficacy of a colloid are nano-particle size and Zeta Potential (ZP). Particle size made with the crude High Voltage Spark ESD method is larger, having an average size of around 100 nm and the smallest around 20-50 nm, far too large a range to pass the blood-organ barriers and therefore unable to combat infections in vital organs. For example, the Blood-Brain Barrier (BBB) is composed of a network of vessels that form a physical, electrostatic and chemical barrier between the brain and blood circulation. Most other organs have their own analogous protective barrier which can be easily damaged by a virus. Diseases of the retina, testis, ovary, prostate, kidney, liver, thymus, thyroid, placenta, pancreas are likely mostly caused by an invading virus that may be pre-programmed to target that specific organ (like the Polio virus), then paves the way for subsequent bacterial growth. Even obesity is thought to be initiated by an adenovirus. Large molecules, like chemotherapy drugs, antidepressants, most antibiotics such as penicillin, do not pass through the BBB easily. These barriers have evolved to prevent the transport of bacteria, large molecules, and most small molecules bigger than 20 nm into the brain or organ. Certain conditions such as mental stress, aging, viral or traumatic inflammation compromise the barrier increasing its permeability. Certain bacteria, although too large, can penetrate because of their rotating spiral structure (spirochaetes) which allows them to act as a power drill. These enter the brain and cause syphilis (Treponema), Lyme (Borrelia), and Leptospirosis. Even with well-maintained equipment the best High Voltage Electric Spark Discharge (ESD) technique of our competitor’s results fall outside of the desired effective range both for smallest particle size and for Zeta Potential. Reported ESD best values for ZP is 30 millivolts (mv) instead of our 60 – 100 mv. ZP must be more than 30 mv to ensure the stability of the nano-particles, otherwise particles agglomerate and fall to the bottom in a few days and also lack the power to zap microbes, especially the spikes of the Coronavirus.